PQQ Capsules

Looking to add a premium, novel ingredient to your daily supplement stack? Naturecan’s PQQ supplement delivers 20mg pyrroloquinoline quinone alongside selenium (as L-Selenomethionine) in a convenient, once-daily vegan capsule. Designed for those looking to add premium PQQ alongside essential selenium to their daily routine - Simple to take, transparently formulated and made to Naturecan’s high-quality standards.

⚠️ This food supplement should be consumed by adults only, excluding pregnant and lactating women.

Key Benefits

• 20mg pyrroloquinoline quinone (PQQ) per serving

• 8.25µg selenium (as L-Selenomethionine) per serving - 15% NRV

• Selenium contributes to the protection of cells from oxidative stress - authorised EU/UK health claim [1]

• Selenium contributes to the normal function of the immune system - authorised EU/UK health claim [1]

• Selenium contributes to normal thyroid function - authorised EU/UK health claim [1]

• Selenium contributes to the maintenance of normal hair and nails - authorised EU/UK health claim [1]

• PQQ disodium salt form for consistent potency

• Authorised as a novel food ingredient in the UK and EU at a maximum daily intake of 20mg

• 60 capsules / 60-day supply

• 1 capsule daily

• Vegan-friendly HPMC capsule shell

• Suitable for vegans

• Third-party tested

• Manufactured to strict quality standards

Product Overview

Wondering about PQQ meaning? PQQ stands for pyrroloquinoline quinone - and knowing what does PQQ stand for helps explain why it has attracted growing scientific interest. It is a naturally occurring, water-soluble compound found in trace amounts in foods such as kiwi fruit, spinach, green tea and fermented soy. PQQ has a unique redox-active molecular structure [2]. It is classified as a novel food ingredient in the UK and EU, authorised for use in food supplements at a maximum daily intake of 20mg. Scientific research into PQQ is ongoing.

Naturecan’s PQQ supplement delivers 20mg pyrroloquinoline quinone per capsule - the maximum permitted daily intake under UK and EU novel food regulations - alongside 8.25µg selenium as L-Selenomethionine. Selenium contributes to the protection of cells from oxidative stress, the normal function of the immune system, normal thyroid function, and the maintenance of normal hair and nails [1]. Together, PQQ and selenium make for a considered dual-ingredient daily supplement.

Whether you are building a longevity-focused supplement stack or looking for a convenient daily vegan capsule, Naturecan’s PQQ supplement fits easily into your routine - one capsule, once daily.

Serving Instructions

Take one capsule daily with a glass of water. Naturecan’s PQQ supplement can be taken with or without food, at a time that suits your routine.

• Consume 1 capsule daily

• Take with a glass of water, with or without food

• Do not exceed the stated recommended daily use

• This food supplement should be consumed by adults only, excluding pregnant and lactating women

• Consult your GP before use if you are on medication or under medical supervision

• This product should not be used as a substitute for a varied, balanced diet and healthy lifestyle

• Store in a cool, dry place out of direct sunlight

• Keep out of reach of young children

Nutritional Information

Serving size: 1 capsule | Servings per pack: 60 | Supply: 60 days | Format: Vegan capsule

NRV = Nutrient Reference Value per UK and EU regulations. PQQ has no established NRV as it is not classified as an essential nutrient.

Ingredients

Bulking Agent (Microcrystalline Cellulose), Glazing Agent (Capsule (Hydroxypropyl Methylcellulose)), Pyrroloquinoline quinone disodium salt, L-Selenomethionine.

Allergens

No allergens declared in the formula. [Allergen cross-contamination statement to be confirmed with manufacturing facility before final publication.]

Suggested Use

Consume 1 capsule daily. Do not exceed the stated recommended daily use. This food supplement should be consumed by adults only, excluding pregnant and lactating women. This product should not be used as a substitute for a varied, balanced diet. Store in a cool, dry place away from direct sunlight. Keep out of the reach of young children.

Certainty Of Purity

At Naturecan, quality and transparency sit at the heart of every formula we develop. Our PQQ supplement has been carefully formulated using high-quality, well-characterised ingredients, with every detail considered from ingredient selection through to final product testing.

Pyrroloquinoline quinone disodium salt has been selected as the active form of PQQ in this formula, offering a stable and consistently potent ingredient. Selenium is included as L-Selenomethionine - an organic form of selenium found naturally in foods such as Brazil nuts, fish and eggs, and one of the better-absorbed selenium forms available. The capsule shell is made from hydroxypropyl methylcellulose (HPMC), making the product suitable for vegans with no gelatin used at any stage.

To ensure the highest standards, Naturecan products follow several key principles:

Third-Party Testing

Where applicable, products are independently tested to verify purity and ingredient quality. Certificate of Analysis available - link to be added once confirmed.

High-Quality Ingredients

We prioritise carefully selected ingredients appropriate to the purpose of the formula. Pyrroloquinoline quinone disodium salt and L-Selenomethionine have both been chosen for their quality and suitability within a daily food supplement.

Science-Backed Formulation

We have formulated at 20mg pyrroloquinoline quinone per capsule, which is the maximum permitted daily intake under UK and EU novel food regulations for this ingredient.

Transparency

Clear labelling, full ingredient declaration and accessible product information help you understand exactly what you are adding to your routine.

Is PQQ Right For You?

If you have been searching for PQQ meaning or asking what is a PQQ supplement, you are not alone - interest in pyrroloquinoline quinone has grown steadily as more people explore longevity-focused wellness routines. Here are some of the people who commonly consider adding a PQQ supplement to their daily stack:

• Individuals building a longevity-focused supplement routine

• Individuals interested in exploring novel supplement ingredients

• People already using NMN, CoQ10, Urolithin A or Resveratrol who want to extend their daily routine

• Those seeking a convenient, once-daily vegan capsule

• Those looking to support normal thyroid function - via the selenium content of this formula

• Those interested in supporting the maintenance of normal hair and nails - via the selenium content of this formula

⚠️ This food supplement should be consumed by adults only, excluding pregnant and lactating women. If you are on medication or under medical supervision, consult your GP before use.

Ingredients Explained

Pyrroloquinoline Quinone (PQQ)

Pyrroloquinoline quinone is a naturally occurring compound originally identified as a cofactor in certain bacterial enzyme systems. It is found in trace amounts in a number of plant foods - including kiwi fruit, green tea, spinach, parsley and green peppers - as well as in human breast milk. In food supplement form, the authorised legal form is pyrroloquinoline quinone disodium salt, which provides a stable source of the compound.

PQQ has a unique redox-active molecular structure. Scientific research on PQQ’s biochemical properties is ongoing [2]. PQQ is classified as a novel food ingredient in the UK and EU, authorised for use in food supplements at a maximum daily intake of 20mg.

Naturecan’s PQQ supplement provides 20mg pyrroloquinoline quinone per capsule - the maximum permitted daily intake under UK and EU novel food regulations.

Selenium (L-Selenomethionine)

Selenium is an essential trace mineral that the body requires for a number of important processes. It is found naturally in foods such as Brazil nuts, fish, eggs, whole grains and sunflower seeds. L-Selenomethionine is an organic form of selenium - the same form found in plant and animal food sources - and is considered one of the better-absorbed forms available in supplement format.

Selenium has a broad range of authorised health claims under UK and EU food supplement regulations [1]. It contributes to:

• The protection of cells from oxidative stress

• The normal function of the immune system

• Normal thyroid function

• The maintenance of normal hair and nails

• Normal spermatogenesis

Naturecan’s formula provides 8.25µg selenium per serving as L-Selenomethionine, contributing 15% of the nutrient reference value (NRV) per daily capsule. For more on supporting immune health day to day, read our guide on how to support your immune system naturally. If you are looking to complement your routine with another daily mineral supplement, Magnesium Bisglycinate is a popular option from the Naturecan range.

Led By Experts & Studies

Scientific Research on PQQ

A number of scientific studies have examined various biochemical parameters in subjects and models where PQQ has been administered. Much of this evidence is preliminary or from animal and cell models. PQQ supplements are food supplements, not medicines, and are not intended to diagnose, treat, cure, or prevent any disease. For a broader overview of how longevity supplements are being researched, see our guide to top longevity trends in 2025.

Study 1: Biochemical Parameters in Human Subjects

A human study by Harris et al. (2013), published in the Journal of Nutritional Biochemistry, examined changes in biochemical markers in healthy adult subjects consuming dietary PQQ. The study observed changes in certain parameters related to cellular metabolism. The authors noted that the findings were preliminary and that further research is needed [2].

Study 2: Cognitive Assessments in Older Adults

A study by Nakano et al. (2012) examined cognitive assessment scores in middle-aged and elderly persons consuming PQQ over a 12-week period. The study observed differences in certain assessment scores between the PQQ and placebo groups. The study was small in scale and its findings are considered preliminary [3].

Study 3: Preclinical Research

A 2024 study published in Frontiers in Aging examined certain cellular parameters in aged mice and D-galactose-induced cell models where PQQ was administered. Researchers observed changes in certain cellular markers in these models. Findings from animal and cell studies cannot be directly extrapolated to humans, and further clinical research is needed [4].

Selenium - Authorised Health Claims

Selenium is a well-established essential mineral with authorised health claims under UK and EU food supplement regulations. It contributes to the protection of cells from oxidative stress, the normal function of the immune system, normal thyroid function, the maintenance of normal hair and nails, and normal spermatogenesis [1].

PQQ supplements are food supplements, not medicines. These summaries are for educational purposes only and do not imply any therapeutic benefit from Naturecan’s PQQ supplement.

Naturecan’s Commitment To Quality

Naturecan was built on the belief that wellness supplements should be science-led, honestly formulated and straightforward to understand. Understanding the real PQQ benefits of transparency and quality starts with knowing exactly what is in your supplement and why. Every product in the range - from foundational vitamins to novel ingredients like PQQ - is developed with the same commitment to ingredient quality, transparent labelling and considered dosing. You can also explore our NMN benefits article to see how we approach the science behind our longevity range.

Our PQQ supplement reflects that approach. We have formulated at 20mg pyrroloquinoline quinone per capsule - the maximum permitted daily intake under UK and EU novel food regulations for this ingredient - alongside a functional, well-absorbed selenium source with multiple authorised health benefits.

By combining third-party testing, high-quality ingredient selection and accessible certificates of analysis, Naturecan gives you the information you need to make confident, informed decisions about the supplements you choose every day.

Frequently Bought Together

Many customers combine Naturecan’s PQQ supplement with other products from the longevity range as part of their daily routine.

CoQ10 - often purchased together by customers building longevity-focused supplement routines.

NMN supplement - a popular NAD+ precursor supplement commonly used alongside PQQ in daily wellness stacks.

Urolithin A - another novel ingredient frequently chosen by those building longevity-focused routines.

Resveratrol - a well-known polyphenol commonly purchased alongside PQQ by longevity supplement users.

Magnesium Bisglycinate - a gentle, well-tolerated daily mineral supplement to complement an active lifestyle and overall wellness routine.

FAQs

What is PQQ?

PQQ meaning: PQQ stands for pyrroloquinoline quinone. If you have been asking what is a PQQ supplement, the answer is that it is a naturally occurring, water-soluble compound found in trace amounts in foods such as kiwi fruit, spinach, green tea, parsley and fermented soy. PQQ has a unique redox-active molecular structure [2]. In the UK and EU, PQQ is classified as a novel food ingredient, authorised for use in food supplements at a maximum daily intake of 20mg. PQQ supplements are food supplements, not medicines.

What does PQQ stand for?

What does PQQ stand for? PQQ stands for pyrroloquinoline quinone. Understanding PQQ meaning helps explain the scientific interest behind it - it is sometimes referred to informally as vitamin-like in scientific literature due to its cofactor activity in certain bacteria, though it is not classified as a vitamin or essential nutrient in humans. The full name - pyrroloquinoline quinone - refers to its distinctive tricyclic ring structure, which gives it its redox-active molecular properties.

What does PQQ do?

PQQ has a unique redox-active molecular structure. Scientific research on its biochemical properties is ongoing [2][3][4]. A number of studies have examined various parameters in subjects and models consuming PQQ - findings are summarised in the scientific research section above. PQQ supplements are food supplements, not medicines, and are not intended to diagnose, treat, cure, or prevent any disease.

What are the benefits of PQQ?

PQQ has no authorised health claims in the UK or EU. Scientific research into its biochemical properties is ongoing. The PQQ benefits most directly relevant to this product relate to the selenium content of the formula. Selenium carries multiple authorised health claims under UK and EU regulations: it contributes to the protection of cells from oxidative stress, the normal function of the immune system, normal thyroid function, and the maintenance of normal hair and nails [1]. PQQ supplements are food supplements, not medicines.

What is the best PQQ supplement?

When looking for the best PQQ supplement, key things to consider include: the form of PQQ used (pyrroloquinoline quinone disodium salt is the authorised, stable form), the dose (20mg is the maximum permitted daily intake under UK and EU novel food regulations), whether the product is third-party tested, and whether it carries a clear, transparent ingredient declaration. Naturecan’s PQQ supplement delivers 20mg pyrroloquinoline quinone disodium salt alongside selenium as L-Selenomethionine in a vegan HPMC capsule, with third-party testing and full ingredient transparency.

Should I take PQQ with CoQ10?

PQQ and CoQ10 are often purchased together by customers building longevity-focused supplement routines. Naturecan’s CoQ10 is available separately if you would like to include both in your daily stack. To learn more about how NMN works alongside other supplement ingredients, read our guide on what is NMN.

What foods contain PQQ?

PQQ is found naturally in a range of foods, including kiwi fruit, spinach, parsley, green peppers, green tea, fermented soy products such as natto, papaya and human breast milk. However, dietary levels of PQQ from food sources are very low - typically in the nanogram to low microgram range per serving. A daily PQQ supplement provides a more concentrated and consistent daily amount than is typically available through food alone.

Is PQQ safe to take daily?

Pyrroloquinoline quinone disodium salt is authorised as a novel food ingredient in the UK and EU at a maximum daily intake of 20mg. Naturecan’s PQQ supplement delivers exactly 20mg per capsule, in line with this authorisation. This food supplement should be consumed by adults only, excluding pregnant and lactating women. If you are on medication or under medical supervision, please consult your GP before use. Always follow the label instructions and do not exceed the stated recommended daily intake.

What does selenium do?

Selenium is an essential trace mineral with a number of authorised health claims under UK and EU food supplement regulations [1]. It contributes to the protection of cells from oxidative stress, the normal function of the immune system, normal thyroid function, the maintenance of normal hair and nails, and normal spermatogenesis. Naturecan’s PQQ supplement includes 8.25µg selenium per serving as L-Selenomethionine - 15% of the daily nutrient reference value.

How long does it take for PQQ to work?

Responses to food supplements vary between individuals and depend on a range of factors including diet, lifestyle and overall health. In human studies examining PQQ, assessment periods have typically ranged from several weeks to a few months. PQQ supplements are food supplements, not medicines, and individual results will vary. Always follow the recommended daily serving instructions.

What does pyrroloquinoline quinone mean?

Pyrroloquinoline quinone is the full chemical name for PQQ. The name describes its molecular structure: a tricyclic ring system consisting of a pyrrole ring fused to a quinoline and a quinone group. This gives PQQ its redox-active molecular properties [2]. PQQ is sometimes referred to informally as vitamin-like in scientific literature due to its cofactor activity in certain bacteria, though it is not classified as a vitamin or essential nutrient in humans. What is a PQQ supplement? It is a food supplement containing pyrroloquinoline quinone disodium salt, authorised as a novel food ingredient in the UK and EU at a maximum daily intake of 20mg.

Is PQQ For You?

• You are building a longevity-focused supplement routine

• You are interested in exploring novel, research-backed supplement ingredients

• You already use NMN, CoQ10, Urolithin A or Resveratrol and want to extend your daily stack

• You are looking for a convenient, once-daily vegan capsule

• You want a transparent, third-party tested supplement formulated to UK and EU novel food standards

• You are an adult who is not pregnant or breastfeeding

References

[1] European Commission (n.d.). EU Register of Nutrition and Health Claims - Selenium authorised claims (Article 13). Available at: https://food.ec.europa.eu/food-safety/labelling-and-nutrition/nutrition-and-health-claims/eu-register-health-claims_en (Accessed: June 2026). Also: UK Retained Regulation (EC) No 1924/2006 on nutrition and health claims made on foods.

[2] Harris, C.B. et al. (2013). ‘Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects’, Journal of Nutritional Biochemistry, 24(12), pp. 2076–2084. Available at: https://doi.org/10.1016/j.jnutbio.2013.07.008 (Accessed: June 2026).

[3] Nakano, M. et al. (2012). ‘Effect of Pyrroloquinoline Quinone (PQQ) on Mental Status of Middle-Aged and Elderly Persons’, Food Style 21, 16(7), pp. 117–125. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277398/ (Accessed: June 2026).

[4] Uchida, K. et al. (2024). ‘Dietary pyrroloquinoline quinone hinders aging progression in male mice and D-galactose-induced cells’, Frontiers in Aging, 5. Available at: https://doi.org/10.3389/fragi.2024.1351860 (Accessed: June 2026).

[5] Jiang, X. et al. (2025). ‘Pyrroloquinoline Quinone Is an Effective Senomorphic Agent to Target the Pro-Inflammatory Phenotype of Senescent Cells’, Aging Cell. Available at: https://doi.org/10.1111/acel.70138 (Accessed: June 2026). Note: verify final publication date before launch.

[6] European Food Safety Authority (2009). Scientific Opinion on the substantiation of health claims related to selenium. EFSA Journal, 7(9), 1220. Available at: https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1220 (Accessed: June 2026).